Optimized voxel-based morphometry in children with developmental dyscalculia

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Optimized voxel-based morphometry in children with developmental dyscalculia

Developmental dyscalculia (DD) is a specific learning disability affecting the normal acquisition of arithmetic skills. Current studies estimate that 3-6% of the school population is affected by DD. Genetic, neurobiological, and epidemiologic evidence indicates that dyscalculia is a brain-based disorder. Imaging studies suggest the involvement of parietal and prefrontal cortices in arithmetic t...

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1 Center for MR-Research, University Children’s Hospital Zurich, Zurich, Switzerland 2 Children’s Research Center, University Children’s Hospital Zurich, Zurich, Switzerland 3 Center of Integrative Human Physiology, University of Zurich, Switzerland 4 Department of Childand Adolescent Psychiatry, DRK-Hospital Westend Berlin, Germany 5 Clinical Psychology and Psychotherapy, University of Potsdam...

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Voxel-based morphometry 1113 elements

An underlying assumption of the above parametric approach is that the process is a = Gaussian field, i.e., its statistical characteristics, including its roughness parameter (or its reciprocal, the smoothness ) ), are the same at each point in the image. The FWHM of the process should be constant in all directions and across all voxels in the image. While these assumptions are reasonable for fu...

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ژورنال

عنوان ژورنال: NeuroImage

سال: 2008

ISSN: 1053-8119

DOI: 10.1016/j.neuroimage.2007.08.045